姓名:李博涵,性别:女,博士,副教授,中国科学院上海药物研究所
一. 论文发表概况:
1. Pyrazolone derivative C29 protects against HFD-induced obesity in mice via activation of AMPK in adipose tissue. Acta pharmacologica Sinica, 2020. Li BH, Zhang M, Duan YN, Shuai L, Jiang HW, Li J, et al.
2. DOT1L Regulates Thermogenic Adipocyte Differentiation and Function via Modulating H3K79 Methylation. Diabetes, 2021. Shuai L#, Li BH#, Jiang HW, Yang L, Li J, Li JY.
3. James. Pinkment: a synthetic platform for the development of fluorescent probes for diagnostic and theranostic applications. Chemical Science, 2020. Weber M#, Han HH#, Li BH#, Odyniec ML, Jarman CF, Yi Zang, et al.
4. SIRT5 regulates brown adipocyte differentiation and browning of subcutaneous white adipose tissue. Diabetes, 2019. Shuai L#, Zhang LN#, Li BH#, Tang CL, Wu LY, Li J, et al.
5. AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue. Frontiers in Physiology, 2018. Wu LY#, Zhang LN#, Li BH#, Jiang HW, Duan YN, Xie ZF, et al.
6. Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1α Promoter Activity. Journal of Natural Products, 2017. Niu B, Ke CQ, Li BH, Li Y, Yi Y, Luo Y, et al.
7. Low-protein/high-carbohydrate diet induces AMPK-dependent canonical and non-canonical thermogenesis in subcutaneous adipose tissue. Redox biology, 2020. Aquilano K, Sciarretta F, Turchi R, Li BH, Rosina M, Ceci V, et al.
8. Protein Encapsulation: A New Approach for Improving the Capability of Small-Molecule Fluorogenic Probes. Chemical Science, 2020. Han HH, Sedgwick A, Shan Y, Li N, Liu TT, Li BH, et al.
二. 课题、获奖及专利:无
三. 著作:无