安天悦

发布者:张棕越发布时间:2021-06-07浏览次数:27


 



 

 

安天悦,博士,教授,硕士研究生导师,毕业于中国科学院植物研究所,暨南大学博士后。主要从事中药萜类活性成分的生物合成途径解析及其合成生物学研究,在抗肿瘤等高价值天然产物微生物细胞工厂的构建及代谢工程策略优化方面积累了丰富的经验。近五年以第一/共同第一作者发表SCI论文8篇,其中中科院一区论文3篇。主持中国博士后科学基金面上项目1项,参与国家自然科学基金项目3项,申报发明专利3项,授权2项。

1. 论文列表

1Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134—mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression. Journal of Ginseng Research. 2021. Wang G#, An T#, Lei C, Zhu X, Yang L, Zhang L*, Zhang R*.(共同第一作者)

2Enzyme promiscuity versus fidelity in two sesquiterpene cyclases (TEAS versus ATAS). 

Enzyme promiscuity versus fidelity in two sesquiterpene cyclases (TEAS versus ATAS). ACS Catalysis. 2020. Zhang F#, An T#, Tang X, Zi J*, Luo H*, Wu R*.(共同第一作者)

3)《Characterization of guaiene synthases from Stellera chamaejasme L. flowers and their application in de novo production of (-)-rotundone in yeast. Journal of Agricultural and Food Chemistry. 2020. An T#, Li L#, Lin Y, Zeng F, Lin P, Zi J*.

4)《Genomic-wide identification and expression analysis of AP2/ERF transcription. Genomic-wide identification and expression analysis of AP2/ERF transcription. Industrial Crops and Products. 2020. Yao W#, An T#, Xu Z, Zhang L, Gao H, Sun W, Liao B, Jiang C, Liu Z*, Duan L*, Ji A*.(共同第一作者)

5Biotechnological production of betulinic acid and derivatives and their applications. Applied Microbiology and Biotechnology. 2020. An T, Zha W, Zi J*.

6)《Reconstruction of the biosynthetic pathway of santalols under control of the GAL regulatory system in yeast. ACS Synthetic Biology. 2020. Zha W#, An T#, Li T, Zhu J, Gao K, Sun Z, Xu W, Lin P, Zi J*.(共同第一作者)

7)《Identification of RoCYP01 (CYP716A155) enables construction of engineered yeast for high-yield production of betulinic acid. Applied Microbiology and Biotechnology. 2019. Huang J#, Zha, W#, An T#, Dong H; Huang Y, Wang D, Yu R, Duan L, Zhang X, Peters RJ*, Dai Z*, Zi J*.(共同第一作者)

8)《Brachypodium distachyon T-DNA insertion lines: A model pathosystem to study nonhost resistance to wheat stripe rust. Scientific reports. 2016. An T, Cai Y, Zhao S, Zhou J, Song B, Bux H, Qi X*.

2. 课题、获奖及专利列表

1.基于合成生物学构建生产α-檀香醇的工程酵母菌(2018M633289),中国博士后科学基金面上项目,2018-052020-09,安天悦(主持)(课题)

2.酿酒酵母工程菌的构建及桦木酸的制备方法. 2019-11-29. 訾佳辰,黄嘉键,朱建勋,安天悦.(专利)

3.高产雅槛蓝醇型倍半萜的酿酒酵母工程菌及其构建方法与应用. 2021-01-29. 訾佳辰,安天悦.(专利)